Venous thrombosis prevention


Venous thrombosis prevention is a means to prevent blood clots from forming in veins within the body.


Different preventative methods can also maintain normal blood flow and therefore enable oxygen and nutrients to reach the cells of the body. Blood clots can be painful and can cause serious damage to tissues and organs. Sometimes, they can cause rapid death. Blood clot prevention can enhance blood flow and can save lives.


Blood clots can form in any vein within the body. Deep vein thrombosis (DVT) can be quite serious. DVT occurs when a blood clot forms in the legs or pelvis. If it is large enough, it can block the blood flow within the vein, cutting off oxygen to the tissues. An embolus or a clot that breaks away from the wall of the blood vessel can travel into the lung, the heart, or the brain where it can disrupt the normal functioning of these organs and become life-threatening. Some blood clots distend the walls of the blood vessel, creating a sac called an aneurysm. Sometimes the aneurysm bursts, causing blood to leak out. If this occurs within the brain, the heart, or the lungs, it can be fatal.

Venous thrombosis can occur for several reasons. The patient may have disease within the blood vessels such as an inflammation of the walls of the vein (phlebitis) or hereditary blood clotting disorders. The patient may also develop blood clots because of other medical conditions such as heart disease, heart failure, stroke, or cancer. They can also occur after surgery or prolonged bed rest or inactivity. People who smoke and take oral contraceptives may be more susceptible to blood clots.

Pulmonary embolism is one of the most common, but highly fatal, blood clots that patients experience. The American Heart Association estimates 600,000 people in the United States develop pulmonary embolisms each year, with 10% of those ending in death. Sometimes there is little or no warning, causing sudden death. About 90% of these embolisms are the result of DVT that forms in the legs or the pelvis and moves into the lung and blocks the pulmonary artery. Most often the DVT occurs in the recovery period after surgery, though there is an alarming trend of DVT events that are the result of airline travel. In 1999, nearly 2,000 Americans, many of them young and fit, died from travel-related DVT strokes. In 2003, NBC reporter David Bloom, who was embedded with the United States Army as he covered the war in Iraq, died of a pulmonary embolism due to his riding in a cramped position for long hours over several days.

Prevention methods

There are several methods physicians use to prevent blood clots. Some use medications, others use mechanical means, and still others require behavioral changes, or a combination of all of these.

Heparin and other blood thinners

Anticoagulants (blood thinners) such as heparin are often prescribed as prophylactics for venous thrombosis. These drugs decrease the clotting ability of the blood. There has been very good success combining heparin and pneumatic compressions stockings, especially for colorectal and cardiac surgery patients.

There are some precautions, however, for using this drug. People who have had an unusual reaction to the drug should not take it, as well as those with allergies to beef and pork. Women who are pregnant and nursing should only use with caution. In addition, certain medications should not be used with heparin. They include aspirin , hyperthyroid medication, and drugs for pain or inflammation.

Mechanical leg pumps (pneumatic compression stockings)

Mechanical stimulation of the calf muscles of the leg can help stimulate blood flow. Many hospitals require all surgery patients, especially those who have abdominal or cardiac surgery, to wear pneumatic compression stockings. These devices wrap around the lower leg from ankle to the knee, some reach as high as the thigh. When plugged in and turned on, a pneumatic device pumps air into chambers within the stocking, which gently tighten around the legs for a few seconds and then are released. This pulsing massage keeps the blood flowing and discourages venous thrombosis.

Compression stockings

Often physicians recommend compression stockings for patients to prevent DVT and edema, and to treat varicose veins and phlebitis. Graduated compression stockings apply more pressure at the ankle and less up the leg and closer to the knee. This pressure prevents backflow of blood and clot formation.


Sitting for long periods or being confined to bed after surgery or during a long illness can slow blood flow, allowing clots to form. As soon as possible after surgery, the patient should move the legs, stand, and begin taking short walks. Travelers or people who work sitting at a desk or computer for several hours at a time should take breaks every hour to get up and move around. While sitting in the confines of an airplane or lying in bed, specific exercises, such as ankle circles or leg lifts, can be done also.


It is important not to restrict fluids when recovering from surgery, traveling, or working for long periods in a seated position. Not only will the body be kept hydrated but drinking fluids will help prevent venous thrombosis. Drinking fluids keeps the blood liquid and moving, discouraging clot formation. Travelers should drink something every hour. This may be difficult since some air carriers may not have frequent beverage service.


The most important preparation that the patient can do is discuss his or her own personal risk of developing blood clots with a physician. If medication is given, the patient should be instructed how to take it and what side effects to look for. Special exercises should be explained to the patient, and a daily walk should be encouraged.

Normal results

Any of these prevention methods can help a patient avoid having a blood clot after surgery or during long periods of inactivity, such as bed rest or while traveling. Travelers and sedentary workers may find moving around and drinking fluids are the best methods for them to prevent blood clots. For patients recovering from surgery, however, a combination of methods is usually necessary. Pneumatic compression pumps with or without a round of heparin may be the best option for surgery patients.



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Dalen, James E. "Pulmonary Embolism: What Have We Learned Since Virchow? Treatment and Prevention." Chest 122 (November 2002): 1801–1818.

Henderson, C. W. "Blood Thinner Helps Treat Clots in Legs and Lungs." Drug Week (February 23, 2001): 8.

Monari, Gina-Louise. "Thrombosis Education." Med Ad News 21 (October 2002): 74–75.

Ramos, Roque, Bakr I. Salem, Maria P. De Pawlikowski, Cordie Coordes, Stephen Eisenberg, and Ronald Leiden-frost. "The Efficacy of Pneumatic Compression Stockings in the Prevention of Pulmonary Embolism after Cardiac Surgery." Chest 109 (January 1996): 82–86.


American Heart Association. 7272 Greenville Avenue, Dallas, TX 75231. (800) 242-8721. .


Wille-Jørgensen, P, M. S. Rasmussen, B. R. Andersen, and L. Borly. "Heparins and Mechanical Methods for Thromboprophylaxis in Colorectal Surgery." The Cochrane Library. Update Software, 2003.

Janie Franz

User Contributions:

I had a hernia in my pelvic removed a few years ago and the doctor ordered pneumatic stockings to wear untilI could get up and go to the bathroom. Well, the nurse left them on until the next day and I was in constant pain. When we left the hospital I couldn't walk without a walker, the pain was so servere.

Since then, I have had leg swelling and pain and the doctors can't find the problem. Could this be my problem five years later.
I had Ventral hernia repair yesterday and they gave me the most painful shot to prevent blood clotting during surgery. After surgery I had mechanical leg pumps (pneumatic compression stockings. I actually liked the pumps on my legs. It definintely helped with circulation and I doubt that these are the culprit of Donald's leg swelling a nd pain.
i have had 4 blood clots in lefft leg started wen i ffell on my but really hard leg swelled double size of outher leg but never hurt had blood clot from groin to ankle an had 3 more clots since then im 8 millagram warphen every day my problem is my ankle upper anklehas constent sores that never heel skin dryes out cracks hurts so bad can hardly walk by the end of the day i wrap it with ace bandage tight stockins do nothing to help i put bag bom on it its like axil grees keeps it moist stops it from drying out at night wen i take off ace bandage it itches so bad i cant stop itching it i itch it till it bleeds iv tried everything to stop itching benadrill steroid creem corazoin 10 anti itch the pain gets so bad sometimes ill take advill tylynoll does nothing how can i stop the itching an the pain with out pain killers the stabbing pain an itching is driving me nuts can you help thanks ron
jes advincula
thank you for this detailed information because helps me in the case of my aunt who's suffering from DVT and its painful. hope to see more studies about this case. Godspeed!

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